业已发现几种职业性肺组织纤维化病变(矽肺、煤工尘肺、石棉肺)中ANA阳性率普遍增加,外周血中的ANA可能与某些致纤维化职业性肺部疾病的发展有关,也可能是机体接触肺泡巨噬细胞吞噬和处理吸入的粉尘所产生的核物质而产生的。不管何种原因,对那些ANA阳性的人中,仍需进一步确定是否与这些人对粉尘的反应更为强烈有关。为此,本文对一组煤矿工进行了 ANA positive rates have been found in several occupational lung fibrosis (silicosis, coal worker pneumoconiosis, asbestosis) and peripheral blood ANA may be associated with the development of certain fibrogenic occupational lung diseases and May be the body’s exposure to alveolar macrophages phagocytosis and treatment of inhaled dust generated by the nuclear material generated. Whatever the reason, for those who are positive for ANA, there is a need to determine further whether these people are more strongly exposed to dust. To this end, this article carried out on a group of coal miners