论文部分内容阅读
本文比较两种避孕针剂对代谢的影响，经用药９个周期，结果显示：Ｍｅｓｉｇｙｎａ注射期间，各项脂质水平均显著下降，胰岛素反应略有增加。停药２周期后，除ＨＤＬ－Ｃ水平仍显著低于注射前水平外，其余均能恢复。Ｃｙｃｌｏｆｅｍ注射期间ＨＤＬ－Ｃ水平亦显著下降，但停药后能恢复到原基础水平，对糖代谢无明显改变。该两种针剂对肝功能皆无影响。本文提示Ｃｙｃｌｏｆｅｍ对脂、糖代谢的影响较Ｍｅｓｉｇｙｎａ为少，可以认为Ｃｙｃｌｏｆｅｍ及Ｍｅｓｉｇｙｎａ是一种安全有效的每月一次避孕针。
This article compared the effects of two types of contraceptives on metabolism. After 9 cycles of treatment, the results showed that during the injection of Mesigyna, the lipid levels decreased significantly and the insulin response slightly increased. After 2 cycles of withdrawal, except for HDL-C levels were still significantly lower than before injection, the rest can recover. HDL-C levels also decreased significantly during Cyclofem injection, but returned to baseline levels after discontinuation, with no apparent change in glucose metabolism. Both injections have no effect on liver function. This article suggests that Cyclofem has less effect on lipid and glucose metabolism than Mesigyna, and Cyclofem and Mesigyna are considered to be safe and effective monthly contraceptives.