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目前终末期肾功能衰竭的发病率逐年增加,同种异体肾移植术已成为治疗的主要手段之一。由于器官来源短缺,活体供肾移植能够部分解决供体不足的问题。活体亲属供肾移植因为长期存活率高,在国外已广泛开展,而国内报道较少。我院于2000年5月和7月成功实施2例,结果如下。 1 临床资料 1.1 一般资料 例1女,17岁,主因慢性肾小球肾炎、慢性肾功能衰竭10个月,常规血液透析6个月,于2000年4月15日入院。检查血型A型,主要组织相容性抗原(HLA)A_(30,-),B_(13,60)DR_(7,15)DQ_(2,6),群体反应性抗体(PRA)3％,淋巴细胞毒交叉配合试验1％。供者,男,45岁,为受者父亲,自愿捐肾,检查血型A型,HLA A_(2,30)B_(13,51)DR_(7,16)DQ_(2,5)。平素身体
At present, the incidence of end-stage renal failure increased year by year, allograft kidney transplantation has become one of the main means of treatment. Living donor kidney transplantation can partially solve the problem of donor deficiencies due to a shortage of organ sources. Living relatives for kidney transplantation because of long-term survival rate has been widely carried out in foreign countries, and less domestic reports. Our hospital in May 2000 and July successfully implemented in 2 cases, the results are as follows. 1 Clinical data 1.1 General Information Example 1 Female, 17 years old, mainly due to chronic glomerulonephritis, chronic renal failure for 10 months, routine hemodialysis for 6 months, on April 15, 2000 admission. The levels of HLA-A30, B13, DR7, DQ2, PRA3, Lymphocyte toxicity cross-fit test 1%. The donor, male, 45 years old, was the father of the recipient and voluntarily donated his kidney to examine the blood type A and HLA A_ (2,30) B_ (13,51) DR_ (7,16) DQ_ (2, 5). Ordinary body