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长期以来认为垂体分泌是直接经海绵窦进入循环系统,但有几种研究表明有些垂体激素可直接输送到脑。作者为证书实这个假说进行了实验。 用清醒和不麻醉绵羊三只和已行垂体切除的一只于精确的间隔期同时从各只绵羊的颈动脉、矢状窦以及颈静脉中抽取血标本。每份标本用放射免疫法测定肾上腺皮质激素的浓度。后用电刺激导致痉挛,激发ACTH的分泌。以观察各种情况下的血中皮质素变化。
Pituitary secretion has long been thought to enter the circulatory system directly through the cavernous sinus, but several studies have shown that some pituitary hormones can be delivered directly to the brain. The author experimented with the hypothesis that the certificate is valid. Blood samples were drawn from the carotid, sagittal sinus, and jugular veins of each of the sheep at exactly the same interval, using one of three clear and non-anesthetized sheep and an excised pituitary gland. The adrenocorticotropic hormone concentration was determined by radioimmunoassay in each sample. After electrical stimulation lead to spasms, stimulate the secretion of ACTH. To observe changes in blood cortisol under various conditions.