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对由益母草、丹参组成的中成药调经益母片的活血化瘀作用机理进行研究。结果：高、中剂量组的调经益母片可减轻大鼠的血小板血栓湿重［（１８．１１±５．７４）ｍｇ、（１８．６０±７．１４）ｍｇ］，与生理盐水组（２４．５０±２．３０）ｍｇ比较，Ｐ＜０．０１和Ｐ＜０．０５；高、中剂量的益母片可降低小鼠血小板的含量［（２８．７３±６．０８）×１０９／Ｌ、（４６．３５±１１．８７）×１０９／Ｌ］，与生理盐水组（８１．１３±１３．４７）×１０９／Ｌ比较均Ｐ＜０．０１；高、中剂量的益母片可延长小鼠出血时间和凝血时间［出血时间分别为（１２．１８±２．４０）ｍｉｎ和（１２．０７±５．５２）ｍｉｎ，与生理盐水组（７．１８±１．５５）ｍｉｎ比较，Ｐ＜０．０１和Ｐ＜０．０５，凝血时间分别为（５．１３±１．４５）ｍｉｎ、（４．０１±１．７０）ｍｉｎ，与生理盐水组（２．４８±０．６８）ｍｉｎ比较，Ｐ＜０．０１和Ｐ＜０．０５］。结果提示，调经益母片的活血化瘀作用机理主要是对抗血小板聚集性和降低血小板含量，抑制血栓形成，以及阻止血液凝固，促进纤溶作用。
The mechanism of promoting blood circulation and phlegm-removing of the proprietary Chinese medicine consisting of Motherwort and Salvia miltiorrhiza was studied. Results: The high and middle doses of Tiaojingyimu tablets can reduce the platelet thrombus wet weight [(18.11±5.74)mg,(18.60±7.14)mg], and the saline group ( 24.50±2.30) mg, P<0.01 and P<0.05; high and middle dose Yimu Tablets can reduce the platelet content in mice [(28.73±6.08)×109 /L,(46.35±11.87)×109/L], P<0.01 compared with saline group (81.13±13.47)×109/L; high and middle dose of motherwort Tablets can prolong the bleeding time and clotting time in mice [bleeding time was (12.18±2.40) min and (12.07±5.52) min, respectively, with saline group (7.18±1.55) Compared with min, P<0.01 and P<0.05, coagulation time was (5.13±1.45) min, (4.01±1.70) min, and saline group (2 .48±0.68) min, P<0.01 and P<0.05]. The results suggest that the mechanism of activating blood circulation and removing blood stasis by regulating menstruation is mainly to fight platelet aggregation and reduce platelet content, inhibit thrombosis, and prevent blood coagulation and promote fibrinolysis.