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目的了解Carnoy液对粘膜组织损伤的性质，为其用于临床治疗提供理论依据。方法以金黄地鼠颊囊作为模型，以Carnoy液作为涂布试剂，药液作用时间为4min，于术后不同时期处死动物，切取标本，进行光镜和透射电镜观察。结果Carnoy液可引起颊囊粘膜上皮坏死脱落，溃疡形成，穿透深度约0.3mm。术后第3周坏死区上度重新形成，胶原纤维及成纤维细胞明显增多。结论Carnoy液是一种烧灼性质较强的物质，将其用于上皮性囊肿治疗，可因上皮破坏而治愈囊肿或降低其复发率。
Objective To understand the nature of Carnoy’s damage to mucosal tissue and provide theoretical basis for its clinical treatment. Methods The golden hamster cheek pouch was used as a model, Carnoy was used as a coating agent, and the action time of the liquid was 4 min. The animals were sacrificed at different times after operation. The specimens were cut and examined by light and transmission electron microscopy. Results The Carnoy solution caused the necrosis of the cheek pouch mucosal epithelium, ulceration, and penetration depth of about 0.3mm. At the third week after operation, the necrotic area was re-formed and collagen fibers and fibroblasts increased significantly. Conclusion Carnoy fluid is a kind of substance with strong cauterization. It can be used for the treatment of epithelial cysts. It can cure cysts or reduce the recurrence rate due to epithelial destruction.