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目的比较夜间血液透析(NHD)和传统血液透析(CHD)患者透析并发症和耐受性的差异。方法选取第二军医大学长征医院NHD和CHD患者各72例,收集两组患者的临床资料,记录透析后恢复时间,并对其透析时低血压及透析后疲乏、瘙痒、肌肉痉挛、头晕、头痛、食欲下降、恶心、呕吐、睡眠障碍等身体不适,以及担心死亡、担心设备故障、失去自由、失去工作等心理上的压力和生活状况共20项指标进行问卷调查。结果与CHD组比较,NHD组患者透析后恢复时间短(P<0.01),透析期间低血压以及透析后疲乏、瘙痒、头晕、头痛、食欲下降、恶心、呕吐等并发症减少(P<0.05,P<0.01),失去自由的人数减少(P<0.01),但担心设备故障的人数增多(P<0.01)。结论 NHD比CHD的血液透析相关并发症少,更能有效提高维持性血液透析患者的耐受性。
Objective To compare the differences in dialysis complications and tolerability in patients with nocturnal hemodialysis (NHD) and conventional hemodialysis (CHD). Methods 72 patients with NHD and CHD from Changzheng Hospital of Second Military Medical University were enrolled in this study. The clinical data of two groups were collected and the recovery time after dialysis was recorded. Hypotension and post-dialysis fatigue, itching, muscle spasms, dizziness, headache , Loss of appetite, nausea, vomiting, sleep disorders and other physical discomfort, as well as worry about death, worry about equipment failure, loss of freedom, loss of work and other psychological pressure and living conditions a total of 20 indicators survey. Results Compared with CHD group, NHD group had shorter recovery time after dialysis (P <0.01), hypotension during dialysis and post-dialysis fatigue, pruritus, dizziness, headache, decreased appetite, nausea and vomiting (P <0.05, P <0.01), the number of people who lost their freedom decreased (P <0.01), but the number of people worried about equipment failure increased (P <0.01). Conclusions NHD has fewer complications related to hemodialysis than CHD, and more effectively improves the tolerability of maintenance hemodialysis patients.