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癌不单是一种局部的病理过程,也是一种整体性的疾病。例如恶病质、免疫无反应性、贫血和高血沉等现象均为恶性生长有关,而同良性生长关系不大,即使良性肿块达到很大的体积。一般认为,增殖的恶性肿瘤产生体液因子影响全身。前列腺素(PGs)是全身组织的激素。多种刺激能使其释放,催化酶能使其迅速灭活。肿瘤组织并不例外,也能够分必前列腺素。如甲状腺髓样癌和其它分必胺肽的肿瘤产生大量的PGs,以致引起诸如潮红和腹泻等临床症状。非嗜银细胞肿瘤,不管是原发的还是继发的均引起 PGS 的产生。原发的或移植的肿瘤在软组织中构成一种机械刺激,引起局部释放 PGs。反
Cancer is not only a local pathological process, but also a whole disease. For example, cachexia, immune non-responsiveness, anemia, and high blood sedimentation are all related to malignant growth, and have little to do with benign growth even if the benign mass reaches a large volume. It is generally believed that proliferating malignant tumors produce humoral factors that affect the entire body. Prostaglandins (PGs) are systemic hormones. A variety of stimuli can release it, and catalytic enzymes can rapidly inactivate it. Tumor tissue is no exception and can be divided into prostaglandins. Pulmonary medullary carcinomas and other tumors that produce amino peptides produce large amounts of PGs, causing clinical symptoms such as flushing and diarrhea. Non-argentocyte cell tumors, whether primary or secondary, cause PGS production. Primary or transplanted tumors form a mechanical stimulus in soft tissue that causes local release of PGs. anti-