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目的:研究白术-白芍不同比例配伍对水提液中有效成分含量的影响,探求药对的最佳配伍比例。方法:运用HPLC切换波长法考察白术、白芍单独水提液与白术-白芍药对不同比例配伍共提液中芍药苷、白术内酯(Ⅰ、Ⅲ)的含量变化情况。结果:与白术、白芍单提液相比,白术-白芍(1∶1,2∶3,1∶2,2∶5,3∶2,2∶1,5∶2)7个比例配伍后芍药苷、白术内酯(Ⅰ、Ⅲ)的含量均有不同程度的提高。结论:白术与白芍配伍后,对彼此有效成分的溶出有一定的促进作用,白术-白芍药对的最佳配伍比例为2∶3。
OBJECTIVE: To study the effect of different proportions of Atractylodes macrocephalae-Radix Paeoniae Alba on the contents of active ingredients in aqueous extract, and to find out the best proportion of compatibility. Methods: The contents of paeoniflorin and atractylenolide (Ⅰ, Ⅲ) in different proportions and compatibility of Atractylodes macrocephalae and Radix Paeoniae Alba - Radix Paeoniae Alba - Paeoniae Alba were studied by HPLC - switched wavelength method. Results: Atractylodes - Radix Paeoniae Alba (ratio of 1: 1, 2: 3, 1: 2, 2: 5, 3: 2, 2: 1, 5: 2) After paeoniflorin, atractylodes lactone (Ⅰ, Ⅲ) levels were increased to varying degrees. Conclusion: Atractylodes macrocephalae and white peony root compatibility, the effective components of each other to promote the dissolution of a certain, Atractylodes - Paeonia pairs compatibility ratio of 2: 3.