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目的总结神经白塞病(NBD)的临床特点。方法回顾性分析2例NBD患者的临床表现和诊治过程,结合国内外文献,复习和总结NBD的临床特点和治疗方法。结果 NBD以中枢神经系统受累为主,可表现为脑实质型和非脑实质型损害,其中以脑干受累最为常见。激素与免疫抑制剂联合治疗可防止疾病复发和减缓疾病进展。结论 NBD是白塞病的严重并发症,临床上早期识别NBD对治疗和预后尤为重要。
Objective To summarize the clinical features of neurogenic Behcet’s disease (NBD). Methods Retrospective analysis of two cases of NBD patients with clinical manifestations and diagnosis and treatment process, combined with domestic and foreign literature review and summarize the clinical features and treatment of NBD. Results NBD was mainly involved in the central nervous system, which could be manifested as parenchymal and non-parenchymal damage in brain. Among them, brain stem involvement was the most common. The combination of hormones and immunosuppressive agents prevents disease recurrence and slows the progression of the disease. Conclusion NBD is a serious complication of Behcet’s disease. Early identification of NBD clinically is particularly important for treatment and prognosis.