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目的:比较不同治疗方式对冠心病合并心脏瓣膜炎的临床指标、生活质量及血清炎性反应的影响。方法:选取2014年2月~2016年6月期间于本院进行治疗的64例冠心病合并心脏瓣膜炎患者为研究对象,将其随机分为对照组和观察组每组各32例,对照组进行常规的药物治疗,观察组则进行外科手术治疗,然后将两组患者治疗前后的心脏功能指标、生活质量及血清炎性指标进行比较。结果:治疗前两组患者的心脏功能指标、生活质量及血清炎性指标比较,P均>0.05,而治疗后观察组的心脏功能指标、生活质量及血清炎性指标均显著地好于对照组,P均<0.05,均有显著性差异。结论:外科手术对冠心病合并心脏瓣膜炎患者血清炎症因子水平及生活质量具有积极的改善作用,适于临床进一步推广应用。
Objective: To compare the clinical effects of different treatment modalities on heart valve disease, quality of life and serum inflammatory response. Methods: Sixty-four patients with coronary heart disease and valvular heart disease who underwent treatment in our hospital from February 2014 to June 2016 were selected as study subjects. They were randomly divided into control group and observation group, with 32 cases in each group and control group The patients in the observation group underwent surgical treatment. The cardiac function, quality of life and serum inflammatory markers before and after treatment were compared between two groups. Results: Before treatment, cardiac function, quality of life and serum inflammatory parameters were compared between two groups before treatment, P> 0.05, and after treatment, the cardiac function, quality of life and serum inflammatory parameters of the observation group were significantly better than the control group , P <0.05, there were significant differences. Conclusion: Surgery has a positive effect on the level of serum inflammatory cytokines and quality of life in patients with coronary heart disease and valvular heart disease. It is suitable for further clinical application.