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目的探讨复方中药渴乐饮对糖尿病大鼠血脂的影响。方法以四氧嘧啶腹腔注射造成大鼠糖尿病模型,观察复方中药渴乐对糖尿病大鼠高脂血症的治疗作用,并与正常对照组、糖尿病对照组及糖尿病胰岛素治疗组的大鼠的血脂水平相比较。以酶法测血脂。组间比较采用方差分析。结果糖尿病大鼠存在严重的脂代谢紊乱,表现为血浆总胆固醇、甘油三酯、低密度脂蛋白升高及高度脂蛋白降低:复方中药渴乐饮可调节脂代谢紊乱,降低糖尿病大鼠血浆总胆固醇、甘油三酯及低密度脂蛋白(P均<0.01),升高高密度脂蛋白(P<0.05),作用较胰岛素明显(P<0.05);复方中药渴乐饮能升高正常大鼠高密度脂蛋白。结论中药复方渴乐饮对糖尿病大鼠的脂代谢紊乱有明显调节作用。
Objective To investigate the effect of compound traditional Chinese medicine Thirity Drink on blood lipid in diabetic rats. Methods Diabetic rat model was induced by intraperitoneal injection of alloxan. The therapeutic effect of TCM on the hyperlipidemia in diabetic rats was observed. The blood lipid levels of rats with normal control group, diabetic control group and diabetic insulin treatment group were observed. Compared. Enzymatic determination of blood lipids. Comparisons between groups were analyzed using analysis of variance. RESULTS: Diabetic rats suffered from severe dyslipidemia, manifested as elevated plasma total cholesterol, triglycerides, low-density lipoprotein, and high lipoprotein levels. Compound Chinese herbal medicine, Thiryeyin, can modulate lipid metabolism and reduce the total plasma of diabetic rats. Cholesterol, triglyceride, and low-density lipoprotein (P<0.01), elevated high-density lipoprotein (P<0.05), more significant than insulin (P<0.05); Increases normal rat high-density lipoprotein. Conclusion Thirty-one herbal compound Thirty-Yue Decoction can significantly regulate lipid metabolism in diabetic rats.