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目的寻求适宜城乡地区子宫颈癌及其癌前病变的筛查方法。方法以我县城乡25～59岁的20 000例已婚妇女作为研究对象,进行以人群为基础的子宫颈癌筛查。对符合条件的妇女进行宫颈刮片检查,刮片阳性及可疑者行电子阴道镜检查,阴道镜检查异常的行宫颈活检,并得到最终的病理学诊断。结果经宫颈刮片检查,NILM 19 149例,ASC 444例,LSIL 273例,HSIL 115例,SCC 19例。851例行阴道镜检查结果:548例无异常,303例在阴道镜下直接活检。活检结果:慢性炎症44例(14.52%),HPV感染58例(19.14%),CINⅠ级52例(17.16%),CINⅡ级18例(5.94%),CINⅢ级27例(8.91%),AIS 69例(22.77%),早期浸润16例(5.28%),SCC 19例(6.27%)。结论这种三阶梯联合检查的宫颈癌筛查是一种经济有效的筛查方法,能使更多的城乡妇女及时得到子宫颈癌的早诊早治。
Objective To seek suitable screening methods for cervical cancer and precancerous lesions in urban and rural areas. Methods A total of 20 000 married women aged 25-59 in urban and rural areas in our county were enrolled in this study. The population-based cervical cancer screening was performed. Cervical smear examination, positive smear and suspicious patients underwent electronic colposcopy and colposcopy abnormal cervix biopsy were performed on eligible women, and the final pathological diagnosis was obtained. Results By cervical smears, there were 19 149 cases of NILM, 444 cases of ASC, 273 cases of LSIL, 115 cases of HSIL and 19 cases of SCC. 851 routine colposcopy results: 548 cases without abnormalities, 303 cases of direct biopsy under colposcopy. Results of biopsy showed that there were 44 cases (14.52%) with chronic inflammation, 58 cases (19.14%) with HPV infection, 52 cases (17.16%) with CINⅠ, 18 cases with CINⅡ (5.94%), 27 cases with CINⅢ Cases (22.77%), early infiltration in 16 cases (5.28%), SCC in 19 cases (6.27%). Conclusion This three-tiered cervical cancer screening test is a cost-effective screening method, which can make more urban and rural women get early diagnosis and treatment of cervical cancer in time.