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目的 :观察“云克”( 99Tc-MDP)治疗恶性肿瘤骨转移的临床疗效及不良反应 ;方法 :取“云克”冻干品 2 0 0mg,用 2 50ml～ 50 0ml生理盐水溶解 ,静脉滴注 3小时 ,连续 5天为一疗程 ,隔一周或隔二周重复治疗 ,2个疗程以上者统计资料分析 ;结果 :“云克”治疗骨转移癌疼痛的总有效率为 82 % ( 55/ 6 7) ,改善活动障碍的有效率为 72 % ( 1 8/ 2 5) ,止痛维持时间平均 1月 ,无明显不良反应 ;结论 :“云克”是一种治疗恶性肿瘤骨转移的有效药物 ,能有效缓解骨痛、改善活动功能障碍、降低血钙、提高患者生活质量 ,可作为肿瘤辅助药物推广应用
Objective: To observe the clinical efficacy and adverse reactions of 99Tc-MDP in the treatment of bone metastases of malignant tumors. Methods: Take 200 g of freeze-dried product of “Yunke” and dissolve it with 250 ml to 500 ml saline solution. Note 3 hours, 5 consecutive days for a course of treatment, repeated every other week or every two weeks of treatment, statistical analysis of more than two courses; results: “Yunke” total bone cancer treatment pain rate of 82% ( 55/ 6 7) The effective rate of improving mobility disorders was 72% (1 8/25), and the average duration of analgesia was 1 month. There was no obvious adverse reaction. Conclusion: “Yunke” is an effective drug for the treatment of bone metastases of malignant tumors. , Can effectively relieve bone pain, improve activity and dysfunction, reduce blood calcium, improve patient quality of life, can be used as an adjuvant drug for cancer promotion