曲霉菌病是由曲霉菌属引起的以呼吸系统感染为主的疾病。此菌可自然感染山羊引起肺曲霉菌病,但对其发病机理及系统病理研究尚未见报道。选15只年龄在2～4岁的雄山羊(实验前确认健康,饲养在消过毒的房间内)分成两组,感染组10只,对照组5只。实验菌种为烟曲霉(来源于曲霉菌病人)。常规预处理后,将菌用含0.05%吐温80的 PBs 缓冲液配成浓度为1.65×10~8孢子数/ml 的菌悬液。感染 Aspergillosis is a disease caused mainly by respiratory system infection caused by Aspergillus. The bacteria can naturally infect goats cause pulmonary aspergillosis, but its pathogenesis and systemic pathology has not been reported. Fifteen male goats, aged 2 to 4 years old (confirmed healthy before experiment and reared in sterilized rooms), were divided into two groups, 10 in the infected group and 5 in the control group. Experimental strain Aspergillus fumigatus (derived from Aspergillus patients). After routine pretreatment, the bacteria were mixed with PBs buffer containing 0.05% Tween 80 to make a bacterial suspension having a concentration of 1.65 × 10 -8 spores / ml. infection