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目的:确定黄连、木香的最佳配伍比例。方法:采用HPLC法测定黄连与木香不同配伍比例中盐酸小檗碱含量,采用小鼠醋酸扭体反应进行镇痛实验,采用小鼠二甲苯耳壳炎症进行抗炎实验,以及试管两倍稀释法进行抑菌实验。结果:黄连与木香的最佳配伍比例为5∶1。结论:本实验综合评估优选出了黄连、木香的配伍比例。
Objective: To determine the optimal compatibility ratio of Coptis chinensis and L. chinensis. Methods: The content of berberine hydrochloride in different proportions of Coptidis Rhizome and Cinnamomum burmanii was determined by HPLC, the analgesic experiment was performed by mouse writhing reaction of acetic acid, the anti-inflammation test was performed by mouse xylene ear mite inflammation, and the test tube double dilution was used. The method of antibacterial experiment. Results: The optimal compatibility ratio of Coptis chinensis and L. chinensis was 5:1. Conclusion: The comprehensive evaluation of the experiment optimized the compatibility ratio of Coptis chinensis and Cinnamomum camphora.