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目的临床观察尿激酶溶栓治疗急性脑梗死的临床有效性。方法大剂量尿激酶超早期溶栓治疗急性脑梗死200例,同时设对照组200例。结果治疗组治愈134例(67%);有效52例(26%);无效10例(5%);恶化4例(2%)。对照组治愈40例(20%);有效112例(56%);无效36例(18%);恶化12例(6%)。两组治愈率经统计学处理有显著性差异P<0.05。结论大剂量尿激酶溶栓治疗急脑梗死,其疗效肯定,超早期溶栓治疗效果显著良好。在严格掌握适应证的情况下,应用比较安全。
Objective To observe the clinical efficacy of urokinase thrombolysis in the treatment of acute cerebral infarction. Methods 200 cases of acute cerebral infarction were treated with ultra-early thrombolysis with high-dose of urokinase and 200 cases of control group. Results The treatment group was cured in 134 cases (67%); effective in 52 cases (26%); ineffective in 10 cases (5%); exacerbation in 4 cases (2%). The control group was cured in 40 cases (20%); effective in 112 cases (56%); ineffective in 36 cases (18%); exacerbation in 12 cases (6%). The cure rate of the two groups was statistically significant difference P <0.05. Conclusion High-dose urokinase thrombolytic therapy of acute cerebral infarction, its efficacy is sure, ultra-early thrombolytic therapy was significantly better. In the strict application of indications, the application of more secure.