国内外都把病理诊断作为肿瘤或其他病变定性的重要方法。一个多世纪来,都是凭经验进行诊断,缺乏定量的客观依据,诊断的准确性、重现性受到限制。如有经验的专家们对非何杰金淋巴瘤分类,同一专家前后分辨符合率达90%～95%,而不同专家的重现率仅为53%～93%。甚至有报道,不同病理学家在肿瘤诊断中的不符合率可高达87%。 Pathological diagnosis is regarded as an important method for the characterization of tumors or other lesions at home and abroad. For more than a century, diagnosis has been based on experience, lacking quantitative and objective evidence, and the accuracy and reproducibility of diagnosis have been limited. If experienced experts classify non-Hodgkin’s lymphomas, the same expert has a 90% to 95% compliance rate before and after, and the recurrence rate for different experts is only 53% to 93%. There have even been reports that the rate of non-conformance among different pathologists in the diagnosis of cancer can be as high as 87%.