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目的探讨肠外肠内营养序贯疗法在妊娠剧吐治疗中的临床应用效果。方法选取深州市医院2012年1月—2014年10月收治的妊娠剧吐患者95例,按照随机数字表法分为观察组(n=46)和对照组(n=49)。观察组采用完全胃肠外营养(TPN)、肠外营养(PN)+肠内营养(EN)序贯营养支持直至正常饮食;对照组给予禁食、补液、补充维生素及电解质,纠正酸碱平衡等常规治疗,比较两组患者的临床治疗效果及尿酮体完全转阴时间、恢复饮食时间、住院时间。结果观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组尿酮体完全转阴时间、恢复饮食时间及住院时间均短于对照组,差异有统计学意义(P<0.05)。结论肠外肠内营养序贯疗法用于妊娠剧吐的营养支持效果显著,可明显缩短患者症状改善时间及住院时间。
Objective To investigate the clinical effect of sequential treatment of parenteral enteral nutrition in the treatment of hyperemesis gravidarum. Methods 95 cases of hyperemesis gravidarum in Shenzhou Hospital from January 2012 to October 2014 were randomly divided into observation group (n = 46) and control group (n = 49) according to random number table. The observation group received complete parenteral nutrition (TPN), parenteral nutrition (PN) + enteral nutrition (EN) sequential nutritional support until normal diet; the control group was given fasting, rehydration, vitamins and electrolytes to correct acid-base balance And other conventional treatment, comparing the clinical efficacy of two groups of patients and complete conversion of urine ketone body time, dietary recovery time, hospital stay. Results The total effective rate of observation group was higher than that of control group (P <0.05). The urinary ketone body complete negative conversion time, recovery time of diet and hospital stay in observation group were shorter than those in control group (P <0.05), and the difference was statistically significant (P <0.05). Conclusion The sequence of parenteral enteral nutrition for nausea and vomiting induced by nausea and vomiting is significant, which can significantly shorten the symptom improvement time and hospitalization time.