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目的:探讨早期综合干预治疗新生儿缺氧缺血性脑病(H IE)疗效。方法:选择中、重度H IE且经过该院新生儿科治疗后<2个月患儿241例,随机分为干预组162例,对照组79例,全部病例均给予输液及高压氧治疗,于预组同时给予视、听、触觉刺激,感知、语言、记忆和动作的系统训练,适当的物理治疗。每月依据0~1岁神经运动检查52项方法检查并记录,6个月评估正常者为康复。结果:干预组康复率为80.86%,对照组康复率为58.23%,两组差异有统计学意义(P<0.01)。结论:早期综合干预治疗可以提高缺氧缺血性脑病的康复率,减少伤残程度。
Objective: To explore the early comprehensive treatment of neonatal hypoxic-ischemic encephalopathy (H IE) curative effect. Methods: One hundred and seventy-two cases of moderate and severe H IE were enrolled in this study. One hundred and seventy-two children younger than 2 months were randomly divided into intervention group (n = 162) and control group (n = 79). All cases were given infusion and hyperbaric oxygen therapy, The group also gives systematic training of visual, listening, tactile stimuli, perception, language, memory and motions, appropriate physical therapy. Per month according to 0 to 1 year old neuromuscular examination of 52 methods to check and record 6 months to assess the normal rehabilitation. Results: The recovery rate was 80.86% in the intervention group and 58.23% in the control group, with significant difference between the two groups (P <0.01). Conclusion: Early comprehensive intervention can improve the recovery rate of hypoxic-ischemic encephalopathy and reduce the degree of disability.