自1975年Kohler和Milstein用细胞融合法开发制备单克隆抗体以来,发现了多种肿瘤相关抗原并制成单克隆抗体,这些单克隆抗体具有识别肿瘤相关的特定物质的性质,不仅可用于检出肿瘤,并可检出心肌损害部位和血栓部位.一、关于单克隆抗体单克隆抗体是免疫球蛋白,有多种类型.在免疫球蛋白中,产生量最多的是IgG,现以IgG为例,来探讨它的结构:它是用二硫键结合的两条长重链基础,形成不能改变的区域;每个重链的一端各自结上短的轻链, Since the development of monoclonal antibodies by the cell fusion method by Kohler and Milstein in 1975, a variety of tumor-associated antigens have been discovered and monoclonal antibodies have been developed. These monoclonal antibodies have the property of recognizing tumor-specific substances and can be used not only for detection but also for detection. Tumor, and can detect myocardial damage and thrombus. First, on the monoclonal antibody monoclonal antibody is an immunoglobulin, there are many types. In immunoglobulin, the largest amount of production is IgG, now IgG as an example , to explore its structure: It is based on two long and heavy chains combined with disulfide bonds to form unchangeable regions; each heavy chain has a short light chain at one end.