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目的探讨食管癌纵隔转移淋巴结患者采用三维适形放疗进行治疗的临床效果及其安全性。方法分析87例食管癌纵隔转移淋巴结患者的资料,将其随机分为研究组44例和对照组43例,研究组患者采用三维适形放疗联合化疗进行治疗,对照组患者则采用常规放疗联合化疗进行治疗,比较两组患者临床治疗效果及其安全性。结果研究组患者有效率为90.9%,对照组为74.4%,研究组患者治疗效果优于对照组(P<0.05);两组患者治疗后各血清肿瘤标志物指标比较,研究组优于对照组(P<0.05);两组不良反应比较对比,差异有统计学意义(P<0.05)。结论食管癌纵隔转移淋巴结患者采用三维适形放疗效果较佳,且安全性也较高,临床可推广应用。
Objective To investigate the clinical effects and safety of three-dimensional conformal radiotherapy in patients with mediastinal lymph node metastasis of esophageal cancer. Methods The data of 87 patients with mediastinal lymph node metastasis from esophageal cancer were analyzed. They were randomly divided into study group (44 cases) and control group (43 cases). The study group was treated with three-dimensional conformal radiotherapy combined with chemotherapy. The control group received conventional radiotherapy combined with chemotherapy For treatment, the clinical efficacy and safety of the two groups were compared. Results The effective rate was 90.9% in the study group and 74.4% in the control group, and the treatment effect in the study group was better than that in the control group (P <0.05). The comparison of the serum tumor markers between the two groups after treatment showed that the study group was better than the control group (P <0.05). There was significant difference between the two groups in adverse reactions (P <0.05). Conclusion The patients with mediastinal lymph node metastasis of esophageal cancer with three-dimensional conformal radiotherapy better, and the safety is higher, the clinical application can be promoted.