硝酸毛果芸香硷滴眼剂,由于处方中加入了磷酸盐缓冲液,含量测定比较困难。目前采用方法已报道的有:中和法、碘量法、四苯硼钠法、双相滴定法、但均不够理想,存在误差大、终点不易掌握和手续烦杂等缺点。我们用“NBS”法测定,取得较理想的结果。测定原理 N-溴代琥珀珗亚胺(简称NBS),是一种反应活性剂,其结构: Pentachlorrine pilose eye drops, due to the prescription by adding phosphate buffer, determination of the content more difficult. Currently used methods have been reported are: neutralization method, iodometric method, tetraphenyl boron sodium method, two-phase titration method, but are not ideal, there is a large error, the end is not easy to grasp and complex procedures and other shortcomings. We use the “NBS” method to measure and achieve better results. Determination of principle N-bromosuccinimide (NBS), is a reactive agent, its structure: