晚近的研究提示,噻嗪类利尿剂对骨质疏松的预防和治疗都起作用.长期应用噻嗪类利尿剂似乎可减少骨折的危险,对老年绝经后妇女和男子能延缓骨质的丢失,同时还可以降低尿钙的排泄,从而减少骨质吸收。然而,上述资料大多来自年青个体,其中许多还是肾石病患者。本文试图探究长期应用噻嗪类药物对老年人骨代谢的影响。方法研究对象为66名白人,男36女30人,年龄70～89岁。其中12例女性和11例男性已服用 Recent studies suggest that thiazide diuretics play a role in the prevention and treatment of osteoporosis.Utilizing long-term thiazide diuretics seems to reduce the risk of fractures and delay the loss of bone mass in post-menopausal women and men, At the same time can also reduce urinary calcium excretion, thereby reducing bone absorption. However, most of the above information comes from young individuals, many of whom are nephrotic patients. This article attempts to explore the long-term use of thiazide drugs on the elderly bone metabolism. Method The study object was 66 white people, 36 males and 30 females, aged 70 to 89 years. Twelve women and 11 men have taken it