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目的：为了卵巢癌手术后免疫治疗的需要，我们用透析法从用癌组织免疫的山羊脾及淋巴结制备了卵巢癌特异性转移因子（ＳＴＦ）。方法：按中国药典及白细胞粘附抑制试验（ＭＴＴ法）对ＳＴＦ的理化性质和免疫学性质进行了检测和鉴定。结果：所制备的卵巢癌ＳＴＦ符合转移因子质量标准，具有对卵巢癌细胞抗原的特异性。在１５例卵巢癌病人的临床应用中，未发现任何毒副反应。结论：用该法制备的卵巢癌ＳＴＦ，可以安全地应用于卵巢癌的免疫治疗。
OBJECTIVE: To develop ovarian cancer-specific transfer factor (STF) from the spleens and lymph nodes of immunized goats with dialysis for the need of immunotherapy after ovarian cancer surgery. Methods: The physicochemical properties and immunological properties of STF were detected and identified according to Chinese Pharmacopoeia and Leukocyte Adhesion Inhibition Test (MTT). RESULTS: The prepared ovarian cancer STF met the quality criteria of the transfer factor and had specificity for the ovarian cancer cell antigen. In the clinical application of 15 patients with ovarian cancer, no toxic side effects were found. Conclusion: The ovarian cancer STF prepared by this method can be safely applied to the immunotherapy of ovarian cancer.