1病例介绍患者女,16岁。因“行走不稳6年”入院。6年前患者逐渐出现行走不稳,伴双上肢不自主抖动,持物时尤甚。症状进行性加重,伴呤诗样语言,性格孤僻,易激惹,身高增长缓慢。入院查体:生命体征平稳,四肢远端湿冷,可见网状青斑,甲床苍白,弓形足;甲状腺Ⅱ度大,峡部可触及直径1 cm左右结节, 1 case description Female patient, 16 years old. Because of “walking unsteady 6 years ” admission. 6 years ago, patients gradually appear unsteady walking, with involuntary jerking upper limbs, holding things even more. Symptoms progressive increase, accompanied by poetic language, eccentric personality, irritability, height growth slow. Admission examination: vital signs stable, extremities wet and cold, showing reticular bruise, a pale bed, bow-shaped foot; thyroid Ⅱ degree, isthmus reach about 1 cm in diameter nodules,