近年来,我国水产养殖业规模不断扩大,集约化和工厂化程度越来越高,但养殖水域污染日益严重导致病害的频繁发生,严重困扰着水产养殖业的健康发展。与此同时,大量抗生素及其它药物的使用,污染了水体,降低了水产品的品质。疫苗对多种疾病尤其是病毒性疾病有显著的预防作用,但特异 In recent years, China’s aquaculture industry has been expanding, intensifying and factorying more and more high. However, the pollution of aquaculture waters is becoming more and more serious, leading to the frequent occurrence of diseases, seriously harassing the healthy development of aquaculture. At the same time, the use of a large number of antibiotics and other drugs has polluted the water and reduced the quality of aquatic products. Vaccine for a variety of diseases, especially viral diseases have a significant preventive effect, but specific