我科最近收治一名肾移植术后6年并发颅内真菌感染的病人,现报道如下。 患者,男性,60岁,病案号106862。于1987年6月行肾移植术,术后以强的松20mg/天,硫唑嘌呤200mg/天抗排斥治疗至今已六年余。强的松服用后立即出现糖尿病,以胰岛素控制。血肌酐随访持续200～250μmol/L之间。1993年5月17日突觉头枕部疼痛,呈持续性刺痛或搏动性跳痛感,轻则头皮疼痛。伴轻度恶心,无发热、呕吐、视物模糊及抽搐。于1993年5月25日收入神经内科。查体:神清,血压20/14kPa,轻度向心性肥胖,心肺阴性,肝脾肋下未及,双下肢无浮肿,神经系统检查无异常。 化验检查:Hb109g/L,WBC7.4×10~9/L,NO.70, Our department recently admitted to a 6-year renal transplant patients complicated with intracranial fungal infection are reported below. Patient, male, 60 years old, case number 106862. Renal transplantation in June 1987, postoperative prednisone 20mg / day, azathioprine 200mg / day anti-rejection treatment has been more than six years. Prednisone immediately after taking diabetes, insulin control. Follow-up of serum creatinine continued between 200 ~ 250μmol / L. May 17, 1993 sudden head and neck occipital pain, persistent pain or pulsatility, pain, ranging from the scalp pain. With mild nausea, no fever, vomiting, blurred vision and convulsions. On May 25, 1993 income neurology. Physical examination: God clear, blood pressure 20 / 14kPa, mild concentric obesity, cardiopulmonary negative, liver and spleen ribs, edema, no lower extremity edema, nervous system examination was normal. Laboratory tests: Hb109g / L, WBC7.4 × 10 ~ 9 / L, NO.70,