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目的探讨部分梅毒高发地市梅毒母婴传播的现况,为制定相关防治策略提供参考根据。方法对经确诊梅毒的孕妇及其所生婴幼儿的个案进行随访、汇总、统计和分析。结果共有155例梅毒感染孕妇有妊娠结局且明确婴幼儿感染状态,其中自然流产2例,死胎4例,先天性梅毒11例。不规范治疗、初检孕周迟、血清滴度高、疗程短是梅毒母婴传播的危险因素。结论应扩大孕产妇和育龄妇女梅毒筛查的覆盖面,加强婚检和产前梅毒的筛查和科学治疗,规范新生儿随访及诊断流程,降低梅毒母婴传播率。
Objective To explore the status of maternal-to-infant transmission of syphilis in some high incidence areas of syphilis and provide reference for formulating relevant prevention and control strategies. Methods The cases of pregnant women diagnosed with syphilis and their infants were followed up, summarized, statistically analyzed. Results A total of 155 cases of syphilis infection in pregnant women have pregnancy outcomes and clear the status of infants and young children, including 2 cases of spontaneous abortion, 4 cases of stillbirth, 11 cases of congenital syphilis. Non-standard treatment, the initial test gestational week late, high serum titer, short course of treatment is a risk factor for transmission of syphilis mother-infant. Conclusion The coverage of syphilis screening should be expanded in pregnant women and women of childbearing age. The screening and scientific treatment of premarital and pre-marital syndrom should be strengthened. The follow-up and diagnosis procedures of newborns should be regulated and the mother-to-child transmission rate of syphilis should be reduced.