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目的:研究血液透析(HD)联合血液灌流(HP)治疗尿毒症顽固性高血压的效果。方法:将30例尿毒症顽固性高血压患者随机分为2组,治疗组与对照组,每组15人。对照组采用单纯HD,每周3次,每次4 h,治疗组在对照组的基础上每两周行HD+HP 1次,治疗2 h撤去灌流器继续HD 2 h,连续治疗12周,观察两组患者治前后血压变化情况。结果:治疗组12周后血压明显下降,与治疗前及对照组比较差异有统计学意义(P<0.01)。结论:HD+HP治疗尿毒症顽固性高血压效果理想,且能预防尿毒症相关并发症,值得临床推广。
Objective: To study the effect of hemodialysis (HD) combined with hemoperfusion (HP) on refractory hypertension in uremia. Methods: Thirty uremic patients with refractory hypertension were randomly divided into two groups: treatment group and control group, with 15 in each group. The control group was treated with HD alone 3 times a week for 4 hours. The treatment group was treated with HD + HP once every two weeks on the basis of the control group, and the HD was withdrawn after 2 hours of treatment. The treatment continued for 2 weeks and continued for 12 weeks. Observed two groups of patients before and after treatment of blood pressure changes. Results: After 12 weeks, the blood pressure of the treatment group decreased significantly compared with that before treatment and the control group (P <0.01). Conclusion: HD + HP treatment of refractory hypertension uremia ideal results, and can prevent uremia-related complications, is worthy of clinical promotion.