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目的:测定枯芩中4种黄酮类药效组分,为建立黄芩类中药与疗效对应的质量标准提供科学依据。方法:采用药对配伍组分-液相色谱综合分析法。结果:药效组分黄芩苷-黄芩素-汉黄芩苷-汉黄芩素含量为(75.83±7.25),(2.72±0.53),(18.62±2.89),(1.44±0.37)mg.g-1。结论:枯芩中黄酮类药效组分黄芩苷-黄芩素-汉黄芩苷-汉黄芩素,比例为52.44:1.89:12.88:1,有清热燥湿作用,与子芩比较有极显著性差异(P<0.01),建议分别建立黄芩类中药药效组分质量评价指标。
OBJECTIVE: To determine the four kinds of flavonoids in Fructus Scutellariae, and provide a scientific basis for establishing the quality standard of Radix Scutellariae which corresponds to the curative effect. Methods: The drug compatibility component - liquid chromatography comprehensive analysis. Results: The contents of baicalin-baicalein-baicalin-wogonin were (75.83 ± 7.25), (2.72 ± 0.53), (18.62 ± 2.89) and (1.44 ± 0.37) mg.g-1, respectively. CONCLUSION: The flavonoids-baicalin-baicalein-baicalin-wogonin in Scutellaria baicalensis Georgi has a ratio of 52.44: 1.89: 12.88: 1, which has the effect of clearing heat and dampness. (P <0.01). It is suggested that the quality evaluation indexes of Chinese medicinal components of Radix Scutellariae should be established respectively.