宫腔粘连(intrauterine adhesions,IUA)作为一种子宫内膜损伤性疾病是临床亟待解决的难题。既往对其研究主要集中在诊断和治疗方面,然而IUA尤其是重度病例的疗效并不理想,因此针对其发病机制的靶向治疗显得非常必要。近些年来随着科学和实验技术的不断发展,对IUA发病机制的研究又有许多新进展。本文就IUA发病机制的研究进展进行简要介绍。 Intrauterine adhesions (IUA) as a kind of endometrial injury is an urgent problem to be solved. Previous studies mainly focused on the diagnosis and treatment, however, the curative effect of IUA, especially in severe cases, is not ideal, so targeting the pathogenesis of the treatment is very necessary. In recent years, with the continuous development of science and experimental techniques, there have been many new developments in the study of the pathogenesis of IUA. This article gives a brief introduction of the research progress of IUA pathogenesis.