不动纤毛综合征(Im—motile cilia syndrome,ICS)是一种具有多发性异常的遗传性疾病,常引起呼吸道病变,男性不育,内脏转位等临床表现,包括Kartagener氏综合征(以下简称卡氏症)和有各种纤毛结构异常的单基因病。纤毛的结构和功能纤毛上皮分布于呼吸道、副鼻窦、中耳和耳咽管等处,精子尾部是一种变异的纤毛 Im-motile cilia syndrome (ICS) is a hereditary disease with multiple abnormalities and often leads to clinical manifestations of respiratory disease, male infertility and visceral metastasis, including Kartagener’s syndrome (hereinafter referred to as Cardiomyopathy) and a variety of ciliated structural abnormalities of single gene disease. Cilia structure and function Cilia epithelial distribution in the respiratory tract, paranasal sinus, middle ear and ear pharynx and other places, sperm tail is a variation of cilia