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为了研究听神经瘤微血管的结构,作者分别对4例内听道内小听神经瘤(直径1～1.5厘米)、3例内听道外大听神经瘤(直径2.5～4.5厘米)及4例正常听神经进行了电子显微镜观察.结果发现:(1)正常听神经的毛细血管腔均被以薄层内皮细胞,只有在细胞核处较厚.内皮细胞的胞浆内有少量细胞器微粒和吸液小泡.毛细血管壁没有孔.内皮细胞间被紧密的结合体所封闭,其基底膜很薄.(2)和正常听神经比较,小听神经瘤的微血管较显著的显示出有许多毛细血管毫无规律的分散在整个肿瘤之中,其独特的表现为内皮细胞肥大、外形不规则,数量多并且堆积在一起,向血管腔内突入,使血管腔变成窄缝,或者由于细胞增殖导致血管腔部分阻塞.有时小血管则由于内皮细胞肥大而形成多管腔.这
In order to study the structure of auditory neuroma microvessels, the authors performed electron microscopy on 4 cases of intra-auditory small acoustic neuromas (diameter 1 to 1.5 cm), 3 cases of extra-auditory large acoustic neuromas (2.5 to 4.5 cm in diameter), and 4 cases of normal auditory nerves. Microscopic observation. The results showed that: (1) The capillary lumen of the normal auditory nerve was covered with a thin layer of endothelial cells only at the nucleus. There was a small amount of organelle particles and aspiration vesicles in the cytoplasm of the endothelial cells. Capillary wall was not Pores. Endothelial cells are closed by tight conjugates and their basement membranes are thin. (2) Compared with normal auditory nerves, the micro-vessels of small acoustic neuromas show more prominently that many capillaries are scattered throughout the tumor. In its unique performance, endothelial cells are hypertrophic, irregularly shaped, multiply in number, and accumulate together. They invade into lumens of blood vessels, making blood vessel lumens narrow, or due to cell proliferation causing partial blockage of blood vessel lumens. Sometimes small blood vessels are Because of the hypertrophy of endothelial cells, multiple lumens form.