脂肪瘤病可在胃肠道任何部位发生,在肠壁多位于粘膜下,较少地在浆膜下.三分之二以上发生在大肠.脂肪瘤病是大肠内仅次于腺瘤病的最常见良性肿瘤.在大宗尸检中0.32-0.5%病例偶然发现大肠脂肪瘤病,有症状的大肠脂肪瘤病则少见.Brunner于1899年首先报告有症状的大肠粘膜下脂肪瘤,此后几篇报告大肠脂肪瘤,包括尸检或其他手术偶然发现,无症状者比有症状者为多.在Mayo医院50年期间外科患者中此病不足0.002%.由于少见,临床表现多样,常被误为更严重的病变如恶性病因而常施行更广泛的手术. Lipoma may occur in any part of the gastrointestinal tract. It is located in the submucosal area of ​​the intestine and less in the serosa. More than two-thirds of the cases occur in the large intestine. Lipoma is secondary to adenomatosis in the large intestine. The most common benign tumors are found in 0.32–0.5% of cases in large autopsy cases with colitis lipomatosis. Symptomatic colorectal lipomatosis is rare. Brunner first reported symptomatic colorectal submucosal lipoma in 1899, followed by several reports. Large-intestinal lipomas, including autopsy and other surgeries, were found by chance to be more common in asymptomatic than symptomatic patients. The disease was less than 0.002% in surgical patients in Mayo Hospital over a 50-year period. Because of the rare clinical manifestations, it was often misinterpreted as more severe. The lesions such as malignancy often perform more extensive surgery.