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我们通过ＰＣＲ ＳＳＣＰ方法 ,分析人脑膜瘤ＰＴＥＮ基因突变高发的第 5和第8外显子 ,并用基因直接测序证实检测结果 ,研究中国人脑膜瘤是否存在ＰＴＥＮ基因的突变和缺失 ,以期为脑膜瘤发病机制的研究提供新的思路。一、材料与方法1 .标本 :34例手术切除并经病理组织学检查证
We analyzed the fifth and eighth exons with high PTEN gene mutations in human meningiomas by PCR SSCP method and confirmed the results by direct sequencing of genes to study whether there is mutation and deletion of PTEN gene in Chinese meningeomas. The study of pathogenesis provides new ideas. First, materials and methods 1 specimens: 34 cases of surgical resection and pathological examination certificate