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子痫前期是一种严重的妊娠并发症,是导致妊娠期母婴发病率及病死率上升的重要原因之一。本文拟从胎盘绒毛滋养细胞入手,观察子痫前期胎盘中RGRN、Bax、Bcl2的表达,并与正常胎盘组织作对比,探讨子痫前期组织中PGRN的表达变化,从而从细胞凋亡的角度探讨子痫前期的发病机制并指导临床治疗。1资料与方法1.1研究对象选取25例轻度子痫前期和25例重度子痫前期和30例正常妊娠的标本。3组孕妇均于行剖宫产术时
Preeclampsia is a serious complication of pregnancy, which is one of the important reasons leading to the increase of maternal morbidity and mortality in pregnancy. This article intends to start from placental trophoblast cells to observe the expression of RGRN, Bax and Bcl2 in placenta of preeclampsia, and compared with normal placenta tissue to explore the changes of PGRN expression in preeclampsia tissue, and then from the perspective of apoptosis The pathogenesis of preeclampsia and guide clinical treatment. 1 Materials and Methods 1.1 study selected 25 cases of mild preeclampsia and 25 cases of severe preeclampsia and 30 cases of normal pregnancy specimens. 3 groups of pregnant women were undergoing cesarean section