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目的探讨高敏C反应蛋白(hs-CRP)是否是老年冠心病的危险因素,及与心血管事件发生率的关系。方法对233名老年冠心病患者,按照hs-CRP水平分成三组,随访18个月,观察心血管事件的发生率。hs-CRP<1.0mg/L为低危组,1.0-3.0mg/L为中危组,>3.0mg/L为高危组。结果各组发生心血管事件的比率分别为高危组36.4%,中危组21.1%,低危组14.8%;p=0.01。高危组的危险性是低危组的2.5倍。发生心血管事件者平均hs-CRP水平比未发生者高(2.77±2.16比1.78±1.76mg/L;p<0.05)。结论HS-CRP是老年冠心病的独立危险因素,并且能预示心血管事件的发生。
Objective To investigate whether high-sensitivity C-reactive protein (hs-CRP) is a risk factor for elderly patients with coronary heart disease and its relationship with the incidence of cardiovascular events. Methods 233 elderly patients with coronary heart disease were divided into three groups according to hs-CRP level and followed up for 18 months to observe the incidence of cardiovascular events. hs-CRP <1.0mg / L for the low-risk group, 1.0-3.0mg / L for the risk group,> 3.0mg / L for the high-risk group. Results The incidence of cardiovascular events in each group were 36.4% in high risk group, 21.1% in intermediate risk group and 14.8% in low risk group, respectively; p = 0.01. The risk of high-risk group is 2.5 times lower risk group. The mean hs-CRP levels in patients who experienced cardiovascular events were higher than those who did not (2.77 ± 2.16 vs. 1.78 ± 1.76 mg / L; p <0.05). Conclusion HS-CRP is an independent risk factor for elderly patients with coronary heart disease, and can predict the occurrence of cardiovascular events.