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间质性膀胱炎是一种难以治愈的慢性病,作者用阿霉素膀胱内灌注治疗了三例经膀胱镜和活体组织病理检查确诊的病人,二男一女,病程均在1年以上,取得了较好的疗效。在无菌操作下经尿道放导尿管,向膀胱内注入溶于50毫升水内的阿霉素50毫克,仰卧俯卧,向两侧卧各15分钟,并尽量保留药物于膀胱内,每周一次共6次,每月1次共1年,或直至症状消失,病变痊愈。前2～3次灌药时症状可能有所加重,可对症治疗,并预先向病人解释清楚,取得合作,症状减轻后则可改为每月灌药1次,开始每3月做内腔镜等检查1次,以后可延长到6～12月复查1次。
Interstitial cystitis is a difficult to cure chronic disease, the author treated with intravesical doxorubicin three cases of patients diagnosed by cystoscopy and biopsy, two men and a woman, the duration of more than 1 year, made Good effect. A transurethral catheter in aseptic operation, into the bladder by injection of 50 ml of doxorubicin dissolved in 50 ml water, supine prone, lying on both sides for 15 minutes, and try to retain the drug in the bladder, every week Once a total of 6 times a month for a total of 1 years, or until the symptoms disappear, the lesion healed. Symptoms may be exacerbated in the first 2 to 3 times when filling, can symptomatic treatment, and explain to the patient in advance to obtain cooperation, reduce the symptoms can be changed to a monthly irrigation 1, beginning every 3 months to do endoscopic And other tests 1, later extended to 6 to December review 1.