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目的:观察改良的新四联疗法治疗HP阳性胃溃疡的临床效果。方法:选取我科门诊收治的45例HP阳性胃溃疡患者,分成观察组(n=23)和对照组(n=22),分别应用新四联疗法和传统四联联疗法治疗,通过电话随访统计患者治疗情况。结果:观察组前2天疼痛缓解率(39.13%,60.87%)明显高于对照组(9.09%,31.82%),P<0.05;治疗结束后第2月溃疡阳性率和HP阳性率(21.74%,26.09%)明显低于对照组(50.00%,59.09%),P<0.05。结论:新四联疗法治疗HP阳性胃溃疡效果显著,可以用于反复发作、HP耐药性高的胃溃疡,是临床值得推广的疗法。
Objective: To observe the clinical effect of modified neo-quadruple therapy on HP-positive gastric ulcer. Methods: Forty-five patients with HP-positive gastric ulcer admitted to our clinic were divided into observation group (n = 23) and control group (n = 22), treated with neo-quadruple therapy and traditional quadruple therapy respectively. Statistics of patient treatment. Results: The pain relief rate (39.13%, 60.87%) in the observation group two days before treatment was significantly higher than that in the control group (9.09%, 31.82%), P <0.05; , 26.09%) was significantly lower than the control group (50.00%, 59.09%), P <0.05. Conclusion: The new quadruple therapy is effective in treating HP-positive gastric ulcer and can be used in recurrent and HP-resistant gastric ulcer. It is a clinically recommended therapy.