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目的观察分析颈动脉粥样硬化治疗中阿托伐他汀钙的临床疗效。方法将2009年1月至2011年6月我院收治的98例符合本次研究要求的颈动脉粥样硬化患者随机平分为两组,其中对照组采用常规治疗,观察组在对照组的基础上追加阿托伐汀钙治疗,比较两组患者的临床疗效。结果对照组颈动脉内膜中层厚度及斑块面积改善效果不明显(P>0.05),观察组改善明显(P<0.05);对照组患者除血清C反应蛋白水平明显降低(P<0.05)外,其他指标均改善不明显(P>0.05),观察组血清C反应蛋白、胆固醇、三酰甘油、高密度蛋白水平明显减低(P<0.05),低密度蛋白水平明显升高(P<0.05)。结论阿托伐他汀钙可有效改善颈动脉粥样硬化水平及血液血脂状况。
Objective To observe and analyze the clinical efficacy of atorvastatin calcium in the treatment of carotid atherosclerosis. Methods From January 2009 to June 2011, 98 cases of carotid atherosclerosis in our hospital were randomly divided into two groups according to the requirements of this study. The control group was treated with conventional therapy. The observation group was based on the control group Additional atorvastatin calcium treatment, the clinical efficacy of two groups of patients were compared. Results The improvement of carotid artery intima-media thickness and plaque area was not obvious in the control group (P> 0.05), and the improvement in the observation group was obvious (P <0.05). The serum C-reactive protein level in the control group was significantly lower than that in the control group (P <0.05). The levels of serum C-reactive protein, cholesterol, triglyceride and high density protein in the observation group were significantly decreased (P <0.05) and the levels of low density protein were significantly increased . Conclusion Atorvastatin calcium can effectively improve the level of carotid atherosclerosis and blood lipid status.