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Primary angle closure glaucoma (PACG) is one of the most common causes of irreversible blindness in Asia and about 80％ of PACG are present in Asia (Song et al., 2017).Genetics plays an important role in the development of PACG (Gramer et al., 2014).Recently, eight common SNPs were found to be strongly associated with PACG (Vithana et al., 2012;Khor et al., 2016) and mutations in MYRF cause high hyperopia accompanied with PACG (Xiao et al.,2019).