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目的评估RT-PCR方法诊断肠道小RNA病毒性脑膜炎的应用价值。方法对象包括脑膜炎组104例和对照组39例,检测脑脊液中肠道小RNA病毒应用RT-PCR方法。结果脑膜炎组的肠道小RNA病毒阳性率为41.3%(43/104),对照组未测出肠道小RNA病毒阳性结果。结论肠道小RNA病毒是导致脑膜炎的重要病原体,RT-PCR方法诊断肠道小RNA病毒性脑膜炎具有较高的应用价值。
Objective To evaluate the value of RT-PCR in the diagnosis of intestinal meningitis virus meningitis. Methods The subjects included meningitis group (n = 104) and control group (n = 39). RT-PCR was used to detect small intestine parvovirus RNA in cerebrospinal fluid. Results The positive rate of intestinal MPV in meningitis group was 41.3% (43/104), but no positive result was found in control group. Conclusions The small picornavirus is an important causative agent of meningitis. RT-PCR is a valuable method for the diagnosis of small-intestine RNA viral meningitis.