目的探讨 BiPAP 呼吸机治疗(COPD)并Ⅱ型呼吸衰竭的疗效。方法将40例慢性阻塞性肺疾病(COPD)患者分为对照组和治疗组。对照组采用常规综合治疗;治疗组在常规综合治疗的基础上加用 BiPAP 呼吸机行无创通气治疗。结果治疗组治疗后患者 pH 值升高,PaCO_2下降,PaO_2和 SaO_2升高,除1例因感染迁延不愈,痰量增多改为气管插管行有创通气外,其余19例均好转出院。对照组5例呼衰加重,其中2例改用有创通气,3例死亡,15例好转出院。结论 BiPAP 呼吸机操作简便,安全有效,值得在临床上推广使用。 Objective To investigate the efficacy of BiPAP ventilator therapy (COPD) and type Ⅱ respiratory failure. Methods 40 patients with chronic obstructive pulmonary disease (COPD) were divided into control group and treatment group. The control group was treated with conventional comprehensive therapy. The treatment group was treated with noninvasive ventilation with BiPAP ventilator on the basis of conventional comprehensive treatment. Results After treatment, the patients in treatment group had higher pH value, PaCO_2 decreased, PaO_2 and SaO_2 increased. Except for 1 case of infection delayed healing and sputum volume increased to invasive ventilation in endotracheal intubation, the other 19 cases were all better discharged. In control group, 5 cases of exacerbation of respiratory failure increased, of which 2 cases switched to invasive ventilation, 3 died, 15 cases were discharged. Conclusion BiPAP ventilator is simple, safe and effective and should be widely used clinically.