因抗肿瘤药物的用量大、用药时间长,故导致消化道出血病例也并非罕见。许多抗肿瘤药物可导致不同程度的骨髓抑制,最初表现为白细胞,尤其是粒细胞减少,随着用药剂量的增加,致使血中白细胞、红细胞及血小板均减少,甚至可发生再生障碍性贫血。血小板减少可引起广泛性多处出血,是抗癌药物治疗的严重并发症之一。值得注意者,不在血小板最低值时,而在血小板回升至30～50×10~9/L时引起出血,其机理不明。临床上表现鼻衄、牙龈出血、蜘蛛膜下腔出 Due to the large amount of anti-tumor drugs, medication for a long time, it led to gastrointestinal bleeding cases are not uncommon. Many anti-tumor drugs can lead to varying degrees of myelosuppression, initially manifested as leukopenia, especially neutropenia, with the dose increased, resulting in decreased blood leucocytes, red blood cells and platelets, and even aplastic anemia. Thrombocytopenia can cause extensive multiple hemorrhage, is one of the serious complications of anti-cancer drug treatment. It is noteworthy that when the platelet is not at the lowest value, bleeding is caused when the platelets rise to 30-50 × 10-9 / L, and the mechanism is unknown. Clinical manifestations of epistaxis, bleeding gums, subarachnoid out