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目的:了解、评估术前介入治疗在骨肿瘤段截除手术中的选择与作用。方法:1992-1997年26例骨肿瘤患者介入治疗后行瘤段切除重建术,观察临床、手术情况,按时随访。结果:1、术前介入治疗总有效率为92%,膝、肩和髋部肿瘤的介入治疗均有良效。2、介入治疗使肿瘤坏死达到Ⅲ级以上,假包膜形成和肿瘤完整切除达到88%。3、严重并发症是3例的皮肤坏死。4、随访显示:局部复发2例,转移2例,死亡5例,本组行保肢术的骨肉瘤患者的2年生存率为53%。结论:术前介入治疗的效果明显,其作用在于:使肿瘤坏死缩小,分界变清,减少肿瘤血供,有利于完整切除肿瘤,减少局部复发、提高手术成功率。主要适用于:(1)恶性骨肿瘤拟行保肢治疗者。(2)良性或中间性骨肿瘤破坏范围大已难以保留患骨、估计肿瘤血供丰富者。
Objective: To understand and evaluate the choice and role of preoperative interventional therapy in the segmentation of bone tumors. METHODS: From 1992 to 1997, 26 patients with bone tumors were treated with interventional therapy and tumor resection and reconstruction were performed. The clinical and surgical conditions were observed and follow-up was conducted on time. Results: 1. The total effective rate of preoperative interventional treatment was 92%. The interventional treatment of knee, shoulder and hip tumors all had good effect. 2. Interventional treatment resulted in tumor necrosis reaching grade III or higher, and pseudocapsule formation and complete tumor resection achieved 88%. 3. Severe complications were skin necrosis in 3 cases. 4. Follow-up showed: 2 cases of local recurrence, 2 cases of metastasis, and 5 cases of death. The 2-year survival rate of osteosarcoma patients undergoing limb salvage surgery was 53%. Conclusion: The effect of preoperative interventional treatment is obvious. Its role is to make the tumor necrosis and shrinkage, clear boundaries and reduce the blood supply of the tumor, which is beneficial to complete resection of the tumor, reduce local recurrence, and improve the success rate of surgery. It is mainly applicable to: (1) Those who are willing to undergo limb salvage therapy for malignant bone tumors. (2) Patients with benign or intermediate bone tumors have a large range of damage and have difficulty in retaining bone and estimating the blood supply of tumors.