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随着与人类免疫缺陷病毒感染有关的卡氏肺孢子虫性肺炎发病的显著增多,需要一种更快速、损伤更少的诊断技术。近年研究表明,检查用诱痰术诱导出的痰液可使55%感染卡氏肺孢子的患者确诊。为了估价近年发展起来的单克隆抗体间接免疫荧光染色是否比姬姆萨染色或甲苯胺兰O 染色在发现痰中卡氏肺孢子虫中更为敏感,作者对此进行了二项前瞻性的研究。在一研究单位采得63例患者的痰标本,有49例最后诊断为卡氏肺孢子虫肺炎,其中46例是通过痰染色而确诊的。下述三种检查方法发现卡氏肺孢子
With a significant increase in the incidence of Pneumocystis carinii pneumonia associated with human immunodeficiency virus infection, a faster, less damaging diagnostic technique is needed. In recent years, studies have shown that the sputum examination induced sputum induced 55% of patients infected with Pneumocystis carinii diagnosis. In order to assess whether indirect immunofluorescence staining of monoclonal antibodies developed in recent years is more sensitive than detection of Giemsa staining or toluidine blue O staining in the detection of Pneumocystis carinii in sputum, the authors conducted two prospective studies . Sputum specimens of 63 patients were collected in a study unit, and 49 of 49 patients were finally diagnosed as Pneumocystis carinii pneumonia. Of these, 46 were confirmed by sputum staining. The following three tests found that the lung Pneumocystis carinii