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检测１２例急性心肌梗塞（ＡＭＩ）、２１例冠心病（ＣＡＤ）和２０例正常对照（ＮＳ）的血清维生素Ｅ（ＶｉｔＥ）、人超氧化物岐化酶（ｈＳＯＤ－１）及血浆过氧化脂质（ＬＰＯ）的代谢产物之一丙二醛（ＭＤＡ）水平。结果显示ＡＭＩ组的ＭＤＡ水平明显高于ＣＡＤ及ＮＳ组，而ＶｉｔＥ水平则显著低于ＣＡＤ及ＮＳ组，二者呈显著负相关（γ＝－０．６７，Ｐ＜０．００１）；ＡＭＩ和ＣＡＤ组的ｈＳＯＤ－１水平均明显低于ＮＳ组，但其两组间无差异，提示ＡＭＩ时ＶｉｔＥ作为主要的抗氧化剂被大量消耗，可能是ＡＭＩ发展的原因之一。
Serum vitamin E (VitE), human superoxide dismutase (hSOD-1) and plasma lipid peroxidation were measured in 12 patients with acute myocardial infarction (AMI), 21 patients with coronary heart disease (CAD) and 20 normal controls (NS) One of the metabolites of substance (LPO), malondialdehyde (MDA). The results showed that the level of MDA in AMI group was significantly higher than that in CAD group and NS group, but the level of VitE in CAD group was significantly lower than that in CAD group (P <0.001) HSOD-1 levels in CAD group were significantly lower than those in NS group, but there was no difference between the two groups, suggesting that VitE as a major anti-oxidant was consumed in AMI, which may be one of the reasons for the development of AMI.