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近年来关于药源性疾病的报道甚多。本刊曾介绍过药物对肝、肾及心脏的不良作用,而对肺的副作用阐述较少。近年国外对此有不少评述,现综合介绍如下。肺是消除药物的场所之一,也可成为药物毒性作用的部位。急慢性药物反应亦可累及肺。动物实验证明,肺能从循环中清除许多内源活性物质,如5-羟色胺、去甲肾上腺素及前列腺素等。并可浓集某些药物,特别是碱性胺类药物,如心得安、丙咪嗪和美散痛等。当
In recent years, many reports on drug-induced diseases. This article has introduced the adverse effects of drugs on the liver, kidneys and heart, and described less side effects of the lungs. In recent years, there are many foreign reviews, are summarized below. Lung is one of the places to eliminate drugs, but also can be a part of the toxic effects of drugs. Acute and chronic drug reactions can also affect the lungs. Animal experiments show that the lungs can remove many endogenous active substances from the circulation, such as serotonin, norepinephrine and prostaglandin. And concentration of certain drugs, especially basic amine drugs, such as propranolol, imipramine and the United States and so on. when