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目的分析系统性红斑狼疮并发心脏损害的临床特点,探讨心脏受累的相关危险因素。方法回顾性分析2005年3月至2013年5月我院系统性红斑狼疮合并心脏损害50例患者的临床资料。结果 139例中有50例存在心脏损害,占35.97%,其中ECG ST-T改变21例;心包积液15例,心肌损害8例,肺动脉高压8例,瓣膜病5例,心律失常4例。心脏损害组与无心脏损害组年龄、性别差异无统计学意义(P>0.05),病程差异有统计学意义(P<0.05)。结论系统性红斑狼疮并发心脏损害常见,可累及心脏各个部位,其中ST-T改变和心包受累最为常见。心脏损害与病程有关。
Objective To analyze the clinical characteristics of systemic lupus erythematosus complicated with heart damage and to explore the related risk factors of cardiac involvement. Methods The clinical data of 50 patients with systemic lupus erythematosus complicated with heart damage in our hospital from March 2005 to May 2013 were retrospectively analyzed. Results Of the 139 cases, 50 cases had heart damage, accounting for 35.97%. Of them, 21 cases had ECG ST-T changes. 15 cases had pericardial effusion, 8 cases of myocardial damage, 8 cases of pulmonary hypertension, 5 cases of valvular disease and 4 cases of cardiac arrhythmia. There was no significant difference in age and sex between the group of heart damage and the group without heart damage (P> 0.05), and the difference of course of disease was statistically significant (P <0.05). Conclusions Systemic lupus erythematosus complicated by heart damage is common and can affect all parts of the heart. ST-T changes and pericardial involvement are most common. Heart damage and duration of the disease.